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Glycolysis is actually important for immune cell function if you block itmacrophages cannot activateThe cell types affected after Tecfidera treatment are just those that are the most glycolitic (such as effector T cells) while Treg cells (among others) are left alone.
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The breakdown of glucose begins with glycolysiswhich is a ten step metabolic pathway yielding two ATP per glucose molecule glycolysis takes place in the cytosol and does not require oxygenIn addition to ATP the end products of glycolysis include two three carbon molecules called pyruvate.
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